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Modern status of pharmacopoeian HPLC analysis and its main shortcomings are discussed. The philosophy "special analytical method for each substance" has to be revised, and as an alternative, a principle of creation of universal methods realized by means of HPLC analyzers is proposed. A prototype of such analyzer is described. The device was designed on the basis of a Milichrome A-02 gradient chromatograph with spectrophotometric detector and reverse phase column.
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| http://dx.doi.org/10.1023/a:1023402130429 | DOI Listing |
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