The relationship between neurovirulence and induction of hydrocephalus was investigated for a measles virus temperature-sensitive mutant and its revertant. The revertant regained the neurovirulence of the parental strain. At appropriate doses the parental, mutant, and revertant strains induced hydrocephalus.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC515613PMC
http://dx.doi.org/10.1128/JVI.18.2.809-811.1976DOI Listing

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