Introduction: Our hypothesis was that a neurocranial suture autograft will, when shielded from dura, grow and be incorporated into the calvarium.
Methods: Growth was monitored by marker separation in three isohistogenic groups of rabbits, between postnatal days 9 and 90. In order to simulate increased neurocapsular expansion force, the left-sided coronal suture of a group of 20 rabbits was immobilised with a resorbable suture on gestational day 25. The other group of 10 rabbits was sham-operated. On postnatal day 9, 10 of the experimental rabbits underwent transplantation of the suture contralateral to the defect resulting from extirpation of the immobilised suture. The transplant was shielded from dural influence by a platinum foil.
Results: The growth of the immobilised coronal sutures was severely impaired, and also that of the contralateral unicoronal sutures to a lesser extent. A significant catch-up of growth occurred in the transplanted unicoronal sutures. Overgrowth occurred at the donor sites.
Conclusion: The results allow us to consider suture transplantation combined with endosteal dura stripping in craniosynostosis surgery.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00381-003-0729-x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Intra-articular Injections of CXCR4-Overexpressing Human Cartilage-Derived Progenitor Cells Improve Meniscus Healing and Protect Against Posttraumatic Osteoarthritis in Immunocompetent Rabbits.
Am J Sports Med
January 2025
Department of Orthopaedics, Warren Alpert Medical School of Brown University/Rhode Island Hospital, Providence, Rhode Island, USA.
Background: Meniscal injuries that fail to heal instigate catabolic changes in the knee's microenvironment, posing a high risk for developing posttraumatic osteoarthritis (PTOA). Previous research has suggested that human cartilage-derived progenitor cells (hCPCs) can stimulate meniscal repair in a manner that depends on stromal cell-derived factor 1 (SDF-1) pathway activity.
Hypothesis: Overexpressing the SDF-1 receptor CXCR4 in hCPCs will increase cell trafficking and further improve the repair efficacy of meniscal injuries.
Effect of dietary supplementation of Lawsonia inermis and Acacia nilotica extract on growth performance, intestinal histopathology, and antioxidant status of broiler chickens challenged with coccidiosis.
BMC Vet Res
January 2025
Department of Poultry and Rabbit Diseases, Faculty of Veterinary Medicine, Aswan University, Aswan, 81528, Egypt.
Avian coccidiosis is one of the many disorders that seriously harm birds' digestive systems. Nowadays the light is shed on using Phytochemical/herbal medicines as alternative natural anti-coccidial chemical-free standards. Consequently, this study aimed to investigate the impact of lawsonia inermis powder (LIP), and Acacia nilotica aqueous extract (ANAE), on growth performance, serum biochemical, antioxidant status, cytokine biomarkers, total oocyst count and intestinal histopathology of broiler chickens challenged with coccidiosis.
View Article and Find Full Text PDFA new way of the Coombs test using flow cytometry-based assay to assess erythrocytes-bound IgG antibodies in the human and rabbit model.
Int J Immunopathol Pharmacol
January 2025
College of Medical Laboratory, Dalian Medical University, Dalian, Liaoning, China.
The Coombs test is important in hematology for detecting erythrocyte-bound IgG antibodies or in serm through agglutination methods, but its sensitivity and specificity are limited. Flow cytometry provides a more precise and sensitive alternative for quantitatively assessing RBC-bound IgG antibodies. This assessment is crucial for evaluating the risk of hemolytic reactions and ensuring safe transfusions.
View Article and Find Full Text PDFOptimization of the density-elasticity relationship for rabbit hindlimb bones.
J Mech Behav Biomed Mater
January 2025
Human Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada; McCaig Institute for Bone and Joint Health, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Department of Mechanical and Manufacturing Engineering, Schulich School of Engineering, University of Calgary, Calgary, Alberta, Canada; Department of Biomedical Engineering, Schulich School of Engineering, University of Calgary, Calgary, Alberta, Canada.
The rabbit is a popular experimental model in orthopaedic biomechanics due to the presence of natural Haversian remodeling, allowing for better translational relevance to the mechanobiology of human bone over traditional rodent models. Although rabbits are often used with computational modeling approaches such as the finite element (FE) method, a validated and widely agreed upon density-elasticity relationship, which is required to make subject-specific predictions, does not exist. Therefore, the purpose of this study was to determine and validate an accurate density-elasticity relationship for rabbit hindlimb bones using mathematical optimization.
View Article and Find Full Text PDFAmniotic Fluid as a Potential Treatment for Vocal Fold Scar in a Rabbit Model.
J Voice
January 2025
Department of Otolaryngology - Head and Neck Surgery, University of Utah, Salt Lake City, UT; Department of Surgery, University Utah, Salt Lake City, UT.
Objectives/hypothesis: Vocal fold (VF) injury and chronic inflammation can progress to scarring, which is notoriously difficult to treat. Human amniotic fluid (AF) has potential for VF wound healing in a rabbit model, and we hypothesized that AF would demonstrate wound healing properties superior to hyaluronic acid (HA) over time.
Study Design: Randomized, controlled trial.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!