A microdialysis technique for continuous subcutaneous glucose monitoring in diabetic patients (part 2).

Biosens Bioelectron

Research and Development Department, A. Menarini Industrie Farmaceutiche Riunite S.r.l., Via Sette Santi, 3-50131, Florence, Italy.

Published: July 2003

The aim of this study was to evaluate the reproducibility, the accuracy and the reliability of a continuous subcutaneous glucose measuring system. The GlucoDay system (A. Menarini I.F.R. S.r.l.-Florence, Italy) is a portable instrument provided with a micro-pump and a biosensor, coupled to a microdialysis system (see part 1). This instrument has demonstrated high reliability coupled with a low degree of invasivity. The profiles of glucose monitoring allow to achieve an excellent knowledge of the real variation of glucose in diabetic patients. The reproducibility study showed a bias lower than 10% between instruments. The accuracy study showed a difference from the reference method lower than 15%.

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http://dx.doi.org/10.1016/s0956-5663(02)00215-4DOI Listing

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