New dihydroalkylhexenones from Lannea edulis.

J Nat Prod

Institute of Pharmacognosy and Phytochemistry, University of Lausanne, BEP, CH-1015 Lausanne, Switzerland.

Published: April 2003

Activity-guided isolation of radical-scavenging compounds from the dichloromethane extract of the root bark of Lannea edulis led to isolation of two known bioactive alkylphenols [cardonol 7 (1) and cardonol 13 (2)], and three new dihydroalkylhexenones were also isolated (3-5). Their structures were elucidated by spectroscopic and chemical methods. The absolute configuration of 4 was determined by the Mosher ester method.

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http://dx.doi.org/10.1021/np0202428DOI Listing

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