Neopterin is an activation marker of macrophages. These cells become activated in bronchial asthma. The aim of the study was to measure serum and BALF neopterin levels in patients with bronchial asthma. The study included 15 patients with moderate, stable bronchial asthma. Serum neopterin levels were normal, while those in BALF were increased. The results of the study seem to indicate that in patients with moderate stable bronchial asthma alveolar macrophages are activated, as shown by increased levels of neopterin in BALF.
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