A study was made into the structural-and-functional status of the osseous tissue in patients with neuroendocrinemetabolic form of the hypothealamic syndrome. Noted in the above patients were abnormalities in the calcium-phosphorous balance which are manifested by a drop in the blood level of calcium and by profound hypercalciuria. All examinees have been shown to present with the osteopenic syndrome formation. Possible causes of development of systemic osteopenia in those patients presenting with neuroendocrinemetabolic form of the hypothalamic syndrome are believed to include, in the first place, hypercorticoidism, hyperprolactinemia, reduction in the estrogen secretion, which might be result in imbalance of processes of bone remodelling involving largely resorption of the bone.

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