Acquired tolerance to temperature stresses is a major protective mechanism. Recent advances have revealed key components of stress signal transduction pathways that trigger enhanced tolerance, and several determinants of acquired tolerance have been identified. Although high and low temperature stresses impose different metabolic and physical challenges, acquired tolerance appears to involve general as well as stress-specific components. Transcriptome studies and other genomic-scale approaches have accelerated the pace of gene discovery, and will be invaluable in efforts to integrate all the different protective and repair mechanisms that function in concert to confer acquired tolerance.
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