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Cooperation between memory systems: acetylcholine release in the amygdala correlates positively with performance on a hippocampus-dependent task. | LitMetric

AI Article Synopsis

  • The study explored how acetylcholine (ACh) release in the amygdala affects spatial working memory tasks in rats.
  • Researchers used a method called in vivo microdialysis to measure ACh levels while the rats performed a spontaneous alternation task.
  • Results showed that higher ACh release in the amygdala was linked to better performance on the memory task, indicating that the amygdala's activation may enhance learning and memory processing in other brain regions.

Article Abstract

The present experiment examined the relationship between release of acetylcholine (ACh) in the amygdala and performance on a hippocampus-dependent spatial working memory task. Using in vivo microdialysis, the authors measured ACh release in rats during testing on a spontaneous alternation task. Amygdala ACh release was positively correlated with performance on the hippocampus-dependent task. These findings suggest that activation of the amygdala promotes processing in other neural systems important for learning and memory.

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Source
http://dx.doi.org/10.1037/0735-7044.117.2.320DOI Listing

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