Thymolipoma is a rare thymic tumor; His frequency is estimated at 2 at 9% of all thymic tumors. His diagnosis usually easy, can be difficult with an unusual radio clinic pattern, but actually get benefice from progress in radiologic investigations especially MRI. We reported a case of a 36-year old woman, admitted for a left pleuro-pneumopathy investigation. Evolution, after antibiotic treatment and pleural effusion draining, was well. However, patient developed systolic aortic murmur and a chest-X-ray cardiomegaly supposing cardiologic dysfunction. But the normality of cardiac sonography, the ascension of diaphragma and non-specific thoracic sonographic pattern, guided to thoracic MRI. This exploration demonstrated a giant thymolipoma, which was confirmed by the histologic examination of a resected mass.

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