AI Article Synopsis
- The study aimed to examine how the nasal cycle behaves over time and how it responds to a nasal decongestant.
- Ten adult volunteers participated in two sessions, with and without the decongestant xylometazoline, while their nasal measurements were taken every 10 minutes for six hours.
- Results showed consistent fluctuations in nasal airflow and resistance, with a notable pattern disruption observed after using the decongestant, indicating that the nasal cycle may not be a universal occurrence and can be altered by nasal spray.
Article Abstract
Objective: We sought to investigate the pattern, duration, and amplitude of nasal cycle and its response to nasal decongestant.
Study Design And Setting: Ten adult volunteers attended 2 sessions (with and without nasal spray of 0.1% xylometazoline) for consecutive examinations by rhinomanometry and acoustic rhinometry every 10 minutes over 6 hours.
Results: A spontaneous fluctuation in nasal minimum cross-sectional area, volume, and nasal resistances (inspiration and expiration) could be observed in every consecutive measurement. A significant negative correlation (r = -0.33 to -0.70, P < 0.05) between both nasal passages was shown in 5 subjects by rhinomanometry and in 2 subjects by acoustic rhinometry but was not detectable after nasal spray with 0.1% xylometazoline.
Conclusion: A spontaneous fluctuation in nasal patency can be documented every 10 minutes with irregular pattern, frequency, and amplitude. Classic nasal cycle is not a universal phenomenon, which can be abolished by the application of decongestant.
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Source |
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| http://dx.doi.org/10.1016/S0194-59980300123-2 | DOI Listing |
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