The effect of clonidine on gastrointestinal side effects associated with ultra-rapid opioid detoxification.

Anesth Analg

*Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center at Dallas, Texas; Department of Anesthesiology, †Cedars-Sinai Medical Center; and ‡Centinela Hospital Medical Center, Los Angeles, California.

Published: May 2003

Clonidine, an alpha(2)-adrenergic agonist, is used to minimize withdrawal symptoms related to ultra-rapid opioid detoxification procedures. These preliminary data suggest that clonidine possesses dose-related antidiarrheal activity.

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http://dx.doi.org/10.1213/01.ANE.0000060451.82578.3ADOI Listing

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