We investigated whether the allocation of rodenticide baiting points to specific structural elements would result in complete rat eradication on livestock farms, as opposed to assigning the baiting points only to places where there were obvious signs of rat activity. The goal was to establish an effective rodent-control program that is easy for untrained persons to conduct.Rat-control strategies were examined on 25 farms in Velen (Muensterland), Germany, where an average of 20% of trapped rats were resistant for bromadiolone according to a blood-clotting response (BCR) test. All farms were investigated for signs of rat activity prior to and after the control measure. Differences in the percentage level of farmer compliance in setting up the baiting points as prescribed were analysed for each type of baiting point and in total, and were compared between the group of farms which achieved complete rat eradication and those which did not. Farms achieving complete eradication had an average of 81% compliance with prescribed control plans, whereas a significantly lower compliance level of only 51% was recorded on farms that did not achieve eradication. A >/=75% level of implementation of the control plan always resulted in complete control success. The new method of bait-point allocation was incorporated into a self-explanatory computer program, which was verified to be effective during a rat-control campaign in the restricted area after an outbreak of classical swine fever near Soltau in northern Germany, in July 2001. This program, which is available on the Internet, enables the creation of individualised rat-control plans, including complete documentation of the control measure.
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http://dx.doi.org/10.1016/s0167-5877(03)00024-2 | DOI Listing |
Nat Commun
January 2025
Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK.
Polioviruses have caused crippling disease in humans for centuries, prior to the successful development of vaccines in the mid-1900's, which dramatically reduced disease prevalence. Continued use of these vaccines, however, threatens ultimate disease eradication and achievement of a polio-free world. Virus-like particles (VLPs) that lack a viral genome represent a safer potential vaccine, although they require particle stabilization.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Marine College, Shandong University, Weihai, Shandong 264209, China. Electronic address:
Managing wounds infected with multi-drug-resistant (MDR) bacteria remains a significant public health challenge in clinical settings. While multifunctional hydrogels are commonly employed to treat skin infections, there is a scarcity of hydrogels that effectively combine cationic guar gum (CG) with both potent antimicrobial and safe therapeutic actions. This study introduces a novel pH responsive, dual-dynamically crosslinked hydrogel (CFC-PDA/Ag), synthesized by crosslinking CG with polydopamine (PDA)-coated silver nanozymes (PDA/PM-AgNPs).
View Article and Find Full Text PDFAdv Healthc Mater
December 2024
College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun, 130012, P. R. China.
Drug Des Devel Ther
December 2024
School of Basic Medical Sciences, Shaanxi University of Chinese Medicine, Xianyang, People's Republic of China.
Background: Precancerous lesions of gastric cancer (PLGC) represent critical stages in gastric cancer progression, with a high risk of malignancy. Current treatments, such as Helicobacter pylori eradication, show limited efficacy in reversing precancerous molecular changes. Zuojin Pill (ZJP), a traditional Chinese medicine, has demonstrated potential for treating digestive disorders and may offer a promising approach for PLGC intervention.
View Article and Find Full Text PDFBiomater Sci
December 2024
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India.
Pathogenic bacterial growth at wound sites, particularly , poses a serious threat during trauma. Delayed treatment can lead to increased inflammation and severe tissue damage. In this study, a chitosan cross-linked polycationic peptide-conjugated graphene-silver (CGrAP) nanocomposite hydrogel film was developed as an antibacterial wound dressing to treat infections.
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