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Impact of monensin, virginiamycin, trace minerals, and yeast combination on animal performance, carcass and meat characteristics of finishing feedlot bulls fed high grain diet.
Trop Anim Health Prod
January 2025
Department of Animal Science, Universidade Estadual de Maringá, Av. Colombo, 5790, Maringá, Paraná, 87020-900, Brazil.
This study was realized to evaluate the influence of monensin, virginiamycin,trace minerals and yeast combination on animal performance, feed efficiency, in situ digestibility, feeding behavior, and carcass and meat characteristics from bulls finished in feedlot fed high-grain diet. A total of 36 (European vs. Nellore) bulls at 24 ± 3.
View Article and Find Full Text PDFUnderstanding the physiological mechanisms and therapeutic targets of diseases: Lipidomics strategies.
Life Sci
January 2025
GAP Center, Graduate School, Heilongjiang University of Chinese Medicine, Harbin, China; International Advanced Functional Omics Platform, Scientific Experiment Center, Hainan Engineering Research Center for Biological Sample Resources of Major Diseases, Key Laboratory of Tropical Cardiovascular Diseases Research of Hainan Province, Hainan Medical University, Xueyuan Road 3, Haikou 571199, China. Electronic address:
As a pivotal branch of metabolomics, lipidomics studies global changes in lipid metabolism under different physiological and pathological conditions or drug interventions, discovers key lipid markers, and elaborates the associated lipid metabolism network. There are a considerable number of lipids in the host, which act on various functional networks such as metabolism and immune regulation. As an indispensable research method, lipidomics plays a key character in the analysis of lipid composition in organisms, the elaboration of the physiological mechanism of lipids, and the decoding of their character in the occurrence and development of diseases by exploring the character of lipids in the host environmental network.
View Article and Find Full Text PDFWound Healing in Older Adults After Major Lower Extremity Amputation.
Ann Vasc Surg
January 2025
Division of Vascular Surgery and Endovascular Therapy, Department of Surgery, Emory University School of Medicine; Surgical and Perioperative Care, Atlanta VA Healthcare System. Electronic address:
Introduction: The higher prevalence of multiple chronic conditions and frailty among older adults may increase the physiologic demand required for wound healing after a major lower extremity amputation (LEA). After below knee amputations (BKA), patients generally have improved prosthetic fitting rates, postoperative ambulation, and quality of life compared to an above knee amputation (AKA). However, the benefit of a BKA must be weighed against the risk of wound complications.
View Article and Find Full Text PDFThe rapid shallow breathing index (RSBI) as a predictor for extubation success in medical and surgical ICU patients: A retrospective cohort study.
Heart Lung
January 2025
College of Nursing, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia; Ministry of the National Guard Health Affairs Riyadh, Saudi Arabia; Medical-Surgical Nursing Department, Faculty of Nursing, Cairo University, Cairo, Egypt.
Background: Endotracheal intubation and mechanical ventilation comprise common life support interventions for patients in intensive care units (ICUs). Premature or delayed extubation increases the risk of morbidity and mortality. Despite following weaning protocols, 10-20 % of patients fail extubation within 48 h.
View Article and Find Full Text PDFOrganoids and microphysiological systems for pharmaceutical research of viral respiratory infections.
Drug Metab Pharmacokinet
November 2024
Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, 606-8507, Japan. Electronic address:
In the pharmaceutical research of viral respiratory infections, cell culture models have traditionally been used to evaluate the therapeutic effects of candidate compounds. Although cell lines are easy to handle and cost-effective, they do not fully replicate the characteristics of human respiratory organs. Recently, organoids and microphysiological systems (MPS) have been employed to overcome this limitation for in vitro testing of drugs against viral respiratory infections.
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