The pathogenetic approach to studying the influence of the environmental factors on the population health does not regard the organism as a "black box" and makes it possible not only to evaluate a scope of risk or to substantiate the parameters of the safe impact degree, it also can be used to specify the biological mechanisms of the influence of the above factors. This can be a foundation for the elaboration of actual methods for the medical-and-biological prevention, treatment and rehabilitation. The pathogenetic approach rests on the knowledge of mechanisms of the organism protection from unfavorable impacts. The protection mechanisms of the organism from the extreme conditions of the Far North, from causative agents of infections, from suspended particles and from toxic substances have been analyzed in the article. The pathogenetic trend of study will enable the centers for the sanitary-and-epidemiological supervision to add the methods for individual health protection to their activity related with public health protection.
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