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Evaluation of Surface Roughness of Multilayered Monolithic Zirconia Following Chairside Adjustment with 3 Different Polishing Systems Sterilized for Multiple Cycles: An In Vitro Study.
Med Sci Monit
March 2025
Department of Prosthetic Dental Sciences, College of Dentistry, Jazan University, Jazan, Saudi Arabia.
BACKGROUND Chairside grinding, finishing, and polishing are essential for smoothing multilayered monolithic zirconia (MMLZ) restorations. Due to rubber matrix hardening, repeated sterilization of finishing and polishing instruments reduces their abrasive effectiveness. This study aimed to evaluate the effects of sterilization cycles on the effectiveness of 3 commercial polishing kits on the surface roughness of MMLZ crown restorations.
View Article and Find Full Text PDFEvaluation the toxic effects of Cobalt-Zinc Ferrite nanoparticles in experimental mice.
Sci Rep
February 2025
Zoology Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt.
Cobalt Zinc ferrite nanoparticles (NPs) were synthesized utilizing the auto-combustion flash method, with the general formula CoZnFeO (x = 0,0.35). This study aimed to evaluate the hepato-renal and systemic toxicity of Cobalt Zinc Ferrite nanoparticles (CZF NPs).
View Article and Find Full Text PDFChronic unpredictable stress exposure disrupts testicular function by modulating germ cell-junctional dynamics and Nrf2/HO-1/IKKβ/NF-κB pathway.
Reprod Toxicol
March 2025
Male Reproductive Physiology Lab., Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi, Uttar Pradesh 221005, India. Electronic address:
The unpredictable nature of stress complicates understanding its relationship with male infertility. In this study, we investigated testicular germ cell and junctional dynamics in male mice following exposure to chronic unpredictable stress (CUS). Adult Parkes male mice were exposed to CUS for 35 days (one complete spermatogenic cycle), with a random stressor (restraint stress, water deprivation, food deprivation, light flashing, wet bedding, cage shaking, or cage tilting) applied once per day in an intermittent and unpredictable manner to avoid repeating the same stimulus on consecutive days.
View Article and Find Full Text PDFIntravitreal chlorhexidine for sterilizing the vitreous cavity in an animal model of bacterial endophthalmitis.
Cutan Ocul Toxicol
December 2024
Edward Harkness Institute of Ophthalmology, Vagelos College of Physicians and Surgeons, Columbia University Medical Center, New York, USA.
Article Synopsis
- The study assesses how effective and safe intravitreal chlorhexidine (CHX) is in sterilizing the vitreous cavity for bacterial endophthalmitis.
- In vitro, CHX concentrations above 6.25 µg/mL effectively killed bacteria, and doses below 200 µg/mL did not harm retinal cells.
- Animal testing showed that CHX concentrations of 20-100 µg/mL could sterilize the vitreous without causing harmful effects, suggesting potential for clinical application.*
So the Bone Flap Hit the Floor, Now What? An In Vitro Comparison of Cadaveric Bone Flap Decontamination Procedures.
Neurosurgery
November 2024
Service de neurochirurgie, Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
Background And Objectives: Over the course of their career, 66% of neurosurgeons will witness someone accidentally dropping a bone flap on the floor during a craniotomy procedure. Although this event is rare, it can have significant consequences for the patient, and little literature is available to guide management of this complication. Our objective was to compare 5 bone flap decontamination protocols for efficacy in reducing bacterial load, with the goal of safely reimplanting the dropped flap.
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