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Background: Donors on testosterone replacement therapy (TRT) may require frequent whole blood donation due to erythrocytosis, but FDA guidelines prevent the transfusion of plasma-based products from these donors. This study surveyed TRT donor testosterone levels in whole blood components and evaluated a possible mitigation strategy with a pathogen reduction technology using UVA light and compound adsorption device (CAD) steps.

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Background: We investigated whether frequent apheresis donors have altered risk of bone fractures, and prescription of osteoporosis medicine//s due to their repeated exposure to citrate anticoagulant.

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