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Drug-induced enterocolitis, a new condition under consideration.
Allergol Immunopathol (Madr)
January 2025
Pediatric Allergy and Pulmonology Unit, Children's University Hospital Reina Sofia, Cordoba, Spain;
Drug-induced enterocolitis syndrome (DIES), little known due to its recent description, is analogous to food protein-induced enterocolitis syndrome (FPIES). Both processes are more frequent in pediatric age and share diagnostic criteria, the main one being the appearance of persistent vomiting 1-4 hours after ingestion of the drug or food, in the absence of IgE-mediated allergy symptoms.
View Article and Find Full Text PDFAnaphylaxis due to green beans (): a new phenotype?
Allergol Immunopathol (Madr)
January 2025
Department of Research and Development, Inmunotek SL, Alcalá de Henares, Madrid, Spain.
Background: Anaphylaxis is a severe allergic reaction with increasing incidence in Europe. It is often caused by food, insect venom, and drugs. White, red, and green beans () are legumes of the family consumed worldwide.
View Article and Find Full Text PDFIntertwined people-nature relations are central to nature-based adaptation to climate change.
Philos Trans R Soc Lond B Biol Sci
January 2025
Faculty of Geosciences and the Environment, Institute of Geography and Sustainability, University of Lausanne, Lausanne 1015, Switzerland.
Adaptation to climate change is a social-ecological process: it is not solely a result of natural processes or human decisions but emerges from multiple relations within social systems, within ecological systems and between them. We propose a novel analytical framework to evaluate social-ecological relations in nature-based adaptation, encompassing social (people-people), ecological (nature-nature) and social-ecological (people-nature) relations. Applying this framework to 25 case studies, we analyse the associations among these relations and identify archetypes of social-ecological adaptation.
View Article and Find Full Text PDFThe evaluation of the serum levels of vitamin D and interleukin-33 in children with atopic dermatitis and its association with diseases severity.
Arch Dermatol Res
January 2025
Cancer Immunology and Immunotherapy Research Center, Ardabil University of Medical Sciences, Ardabil, Iran.
Introduction: Atopic dermatitis (AD) is a chronic inflammatory disease characterized by increased skin sensitivity to environmental elements, mediated by CD4 T helper cells (Th2). Interleukin-33 (IL-33) plays a critical role in exacerbating symptoms in inflamed tissues. Conversely, vitamin D has been shown to induce antimicrobial peptides and suppress the inflammatory response.
View Article and Find Full Text PDFSuccessful Desensitization to Irinotecan in a Patient with Metastatic Esophageal Squamous Cell Carcinoma and a History of Anaphylaxis in Response to Irinotecan-Case Report and Literature Review.
J Clin Med
December 2024
Allergology Department, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
is a topoisomerase I inhibitor used for the treatment of various cancers, such as gastrointestinal, pancreatic, pulmonary, ovarian, and cervical cancers. Among chemotherapy agents, it represents a rare trigger of drug hypersensitivity reactions, with few cases being reported until today. We present the case of a patient with metastatic esophageal cancer and a history of -induced grade IV (WAO classification) anaphylaxis.
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