The evaluation of structure-activity relationships associated with the modification of the R115777 quinolinone ring moiety displaying potent in vitro inhibiting activity is described.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s0960-894x(03)00180-x | DOI Listing |
Publication Analysis
Top Keywords
5-imidazolyl-quinolinones -quinazolinones
4
-quinazolinones -benzo-azepinones
4
-benzo-azepinones farnesyltransferase
4
farnesyltransferase inhibitors
4
inhibitors evaluation
4
evaluation structure-activity
4
structure-activity relationships
4
relationships associated
4
associated modification
4
modification r115777
4
Similar Publications
5-imidazolyl-quinolinones, -quinazolinones and -benzo-azepinones as farnesyltransferase inhibitors.
Bioorg Med Chem Lett
May 2003
Medicinal Chemistry Department, Johnson & Johnson Pharmaceutical Research & Development, Campus de Maigremont BP615, 27106 Val de Reuil, France.
The evaluation of structure-activity relationships associated with the modification of the R115777 quinolinone ring moiety displaying potent in vitro inhibiting activity is described.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!