Connective tissue turnover plays a prominent role in tumour growth and metastasis. We followed serum levels of seven connective tissue parameters in 37 patients with colorectal cancer metastatic to the liver prior to and during chemotherapy. Serum samples with episodes of tumour control (n=112) showed an increase of matrix metalloproteinase-2 (MMP-2) (P
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747566 PMC http://dx.doi.org/10.1038/sj.bjc.6600832 DOI Listing Publication Analysis
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