Clinical aspects of epileptic psychosis in Brazil.

Epilepsy Behav

Institute and Department of Psychiatry, University of São Paulo, Rua Campevas 447, Perdizes, São Paulo, SP CEP 05016-010, Brazil.

Published: April 2003

AI Article Synopsis

  • The study examined 38 Brazilian outpatients with epileptic psychosis, using various clinical tools to gather data on their conditions.
  • Findings indicated that epilepsy usually began in childhood (average age 9.3), preceding the onset of psychosis by about 18 years (average age 27.4), and most cases had temporal lobe epilepsy.
  • The research highlighted significant psychiatric issues such as frequent admissions, suicide attempts, and a postpsychosis decline in functionality, with mesial temporal sclerosis noted as a common factor among participants.

Article Abstract

We investigated a series of patients with epileptic psychosis in Brazil and compared our findings with those of other authors. We evaluated 38 outpatients with epileptic psychosis with a semistructured clinical interview, Annett inventory for hand dominance, international classifications for seizures and syndromes, and DSM-IV for psychosis diagnoses. We studied course and outcome for epilepsy and psychosis. Gender distribution was approximately even. Epilepsy and psychiatric disorders among relatives and early CNS insults in personal histories were frequent findings. Mean age of epilepsy onset was 9.3 years. Epilepsy started before psychosis in all cases, and evolved to clinical refractoriness. There was a predominance of temporal lobe epilepsy. Mean age of psychosis onset was 27.4 years, after a mean duration of epilepsy of 18.1 years, with predominance of schizophrenic presentations with interictal onset, frequent psychiatric admissions, suicide attempts, and postpsychosis functional decline. Tumors or lesions of an embryologic nature were uncommon, but mesial temporal sclerosis was frequent.

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Source
http://dx.doi.org/10.1016/s1525-5050(03)00031-3DOI Listing

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