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Interplay of SHH, WNT and BMP4 signaling regulates the development of the lamina propria in the murine ureter.
Development
January 2025
Institute of Molecular Biology, Hannover Medical School, 30625 Hannover, Germany.
In the mammalian ureters, the lamina propria presents as a prominent layer of connective tissue underneath the urothelium. Despite its important structural and signaling functions, little is known how the lamina propria develops. Here, we show that in the murine ureter, the lamina propria arises at late fetal stages and massively increases by fibrocyte proliferation and collagen deposition after birth.
View Article and Find Full Text PDFUtilization of the QuPath open-source software platform for analysis of mammalian spermatogenesis.
Biol Reprod
January 2025
Department of Anatomy and Cell Biology, Brody School of Medicine, East Carolina University, Greenville, NC USA.
The adult mammalian testis is filled with seminiferous tubules, which contain somatic Sertoli cells along with germ cells undergoing all phases of spermatogenesis. During spermatogenesis in postnatal mice, male germ cells undergo at least 17 different nomenclature changes as they proceed through mitosis as spermatogonia (=8), meiosis as spermatocytes (=6), and spermiogenesis as spermatids (=3) [1-6]. Adding to this complexity, combinations of germ cells at each of these stages of development are clumped together along the length of the seminiferous tubules.
View Article and Find Full Text PDFHelping parents to cope with infant regulatory disorders.
Front Child Adolesc Psychiatry
March 2024
Research Department of Behavioural Science and Health, University College London, London, United Kingdom.
The term Regulatory Disorders (RDs) refers to infants and young children who cry a lot, have poorly organised sleep-waking, or whose feeding is impaired. The characteristic they share is a failure to acquire autonomous self-control of these key behaviours, which most children develop in the first postnatal year. The concept of RDs is helpful in highlighting this question of how infant self-regulation is, or isn't, accomplished, in drawing these characteristics together and distinguishing them from others, and in focusing research and clinical attention on a common, but relatively neglected, set of concerns for families.
View Article and Find Full Text PDFEffective Treatment With Oral Propranolol for Congenital Intracranial Hemangioma in a Neonate: A Case Report and Literature Review.
Cureus
December 2024
Department of Pediatrics, The Jikei University School of Medicine, Tokyo, JPN.
Congenital intracranial hemangiomas are rare benign vascular tumors that develop before birth. Although various treatments, including surgery, steroids, interferon-α, thalidomide, bevacizumab, or propranolol, have been reported, no standard therapy has been established. We report the case of a neonate with congenital intracranial hemangioma and central nervous system symptoms requiring therapeutic intervention.
View Article and Find Full Text PDFHindlimb muscles of the Emperor Penguin Aptenodytes forsteri (Aves, Sphenisciformes) at different postnatal ontogenetic stages.
J Anat
January 2025
División Paleontología Vertebrados, Museo de La Plata, Facultad de Ciencias Naturales y Museo, Universidad Nacional de La Plata, Buenos Aires, Argentina.
The Emperor Penguin Aptenodytes forsteri is the largest living species of penguin, found exclusively in Antarctica, and is unique in breeding during the winter. Consequently, fewer anatomical studies have been conducted on this species over time compared to others. This study aims to provide an updated and comprehensive description of the hindlimb musculature of Aptenodytes forsteri.
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