We have developed an efficient program, the Perfect Phylogeny Haplotyper (PPH) that takes in unphased population genotype data, and determines if that data can be explained by haplotype pairs that could have evolved on a perfect phylogeny.
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http://dx.doi.org/10.1093/bioinformatics/btg078 | DOI Listing |
Proc Natl Acad Sci U S A
January 2025
Division of Biological Sciences, University of Montana, Missoula, MT 59812.
bioRxiv
December 2024
Institute of Ecology and Evolution, University of Edinburgh, Edinburgh, UK.
In Bayesian phylogenetic and phylodynamic studies it is common to summarise the posterior distribution of trees with a time-calibrated consensus phylogeny. While the maximum clade credibility (MCC) tree is often used for this purpose, we here show that a novel consensus tree method - the highest independent posterior subtree reconstruction, or HIPSTR - contains consistently higher supported clades over MCC. We also provide faster computational routines for estimating both consensus trees in an updated version of TreeAnnotator X, an open-source software program that summarizes the information from a sample of trees and returns many helpful statistics such as individual clade credibilities contained in the consensus tree.
View Article and Find Full Text PDFMolecules
November 2024
Key Laboratory for Biodiversity Conservation in Karst Mountain Area of Southwestern China, National Foresty and Grassland Administration, Guiyang 550005, China.
Bibenzyl compounds are one of the most important bioactive components of natural medicine. However, as a traditional herbal medicine is rich in bibenzyl compounds and performs functions such as acting as an antioxidant, inhibiting cancer cell growth, and assisting in neuro-protection. The biosynthesis of bibenzyl products is regulated by bibenzyl synthase (BBS).
View Article and Find Full Text PDFMol Biol Evol
November 2024
Institut de Systématique Evolution, Biodiversité (ISYEB UMR7205-CNRS, Muséum National d'Histoire Naturelle, SU, EPHE, UA), Paris 75005, France.
Felsenstein's bootstrap is the most commonly used method to measure branch support in phylogenetics. Current sequencing technologies can result in massive sampling of taxa (e.g.
View Article and Find Full Text PDFBMC Plant Biol
November 2024
College of Agriculture and Life Sciences, Shanxi Datong University, Datong, Shanxi, China.
Background: Astragalus membranaceus (Fisch.) Bunge is one of the most well-known tonic herbs in traditional Chinese medicine, renowned for its remarkable medicinal value in various clinical contexts. The corresponding chloroplast (cp) and nuclear genomes have since been accordingly sequenced, providing valuable information for breeding and phylogeny studies.
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