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Pancreatic masses in children: a single-center experience over two decades.
Eur J Pediatr
October 2024
Division of Pediatric General Surgery, Stanford University, Palo Alto, CA, USA.
Unlabelled: Pancreatic masses are extremely rare in pediatric patients, with limited data available. This lack of data makes the diagnosis and management of these tumors in children extremely challenging. Therefore, we aimed to describe the presentations, clinical course, and outcomes of children with pancreatic tumors at our center.
View Article and Find Full Text PDFPresentation, Diagnosis, and Treatment of a Sporadic Gastrinoma With Liver Metastases.
Cureus
May 2024
General Surgery, Brookdale University Hospital Medical Center, Brooklyn, USA.
Article Synopsis
- - A gastrinoma is a rare but serious tumor that produces gastrin, which can cause symptoms like anemia, weight loss, and diarrhea, complicating early detection.
- - These tumors often spread to the liver, and surgery is typically necessary to remove both the primary tumor and any metastases for a chance at a cure.
- - This report discusses a case involving a 59-year-old woman with anemia and gastrointestinal bleeding, revealing a pancreatic gastrinoma with extensive liver metastases, along with the treatment approach taken to improve her survival odds.
A Case of a Metastatic Pancreatic Neuroendocrine Tumor: A Surgical Conundrum Wrapped in Functionality's Embrace.
Cureus
March 2024
First Department of Surgery, Laikon General Hospital, National and Kapodistrian University of Athens, Athens, GRC.
This case study reports a rare case of a non-functioning metastatic pancreatic neuroendocrine tumor (pNET) transforming into a functioning pNET. A 59-year-old male, previously treated with distal pancreatectomy, splenectomy, lymph node dissection, liver metastasectomy, and pharmacotherapy, presented with weakness, hypoglycemia, and daily episodes of watery diarrhea. A functioning neuroendocrine liver metastasis expressing insulin and gastrin was identified.
View Article and Find Full Text PDFNeoadjuvant Peptide Receptor Radionuclide Therapy in a Rare Case of Pediatric Primary Hepatic Gastrinoma.
Clin Nucl Med
April 2024
From the Departments of Pediatric Gastroenterology and Hepatology.
Gastrinomas with predilection for the adult male population are located in the gastrinoma triangle (>90%). Primary hepatic gastrinoma especially in pediatric population is very rare. Peptide receptor radionuclide therapy has shown benefit in metastatic gastroenteropancreatic neuroendocrine tumors (NETs) with an increasing interest in expanding its role as neoadjuvant treatment modality to improve the surgical candidature in inoperable NETs.
View Article and Find Full Text PDFTwo cases of pancreatic neuroendocrine tumors with ectopic ACTH syndrome during their disease course.
Clin J Gastroenterol
April 2024
Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.
Pancreatic neuroendocrine tumors (PanNETs) are rare malignant tumors that occur in the pancreas. They are divided into functioning and non-functioning tumors based on the presence or absence of their specific hormonal hyper-expression symptoms. Adrenocorticotropic hormone (ACTH)-producing PanNETs are rare, functional tumors, and their clinical characteristics and outcomes have not been well reported.
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