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Reducing time for vascular access salvage: initial results from a single institution's clinical practice improvement programme.
BMJ Open Qual
March 2025
Department of General Surgery, Tan Tock Seng Hospital, Singapore.
Background: One of the most common causes of arteriovenous fistula (AVF) and/or arteriovenous graft (AVG) failure is thrombosis. Guidelines recommend early AVF salvage within 24-48 hours. Our institution reported poor compliance with these recommendations, with a median of 3 days prior to vascular access (VA) salvage.
View Article and Find Full Text PDFRhythmic auditory cues improve gait asymmetry during unobstructed walking in people with Parkinson's disease but have no effect on obstacle avoidance - AsymmGait-Parkinson study.
Front Aging Neurosci
February 2025
Human Movement Research Laboratory (MOVI-LAB), Department of Physical Education, School of Sciences, São Paulo State University (UNESP), Bauru, Brazil.
Introduction: This study investigated the influence of rhythmic auditory cues (RAC) on gait asymmetry (GA) during unobstructed and obstacle avoidance walking in people with Parkinson's disease (PD) and neurologically healthy individuals.
Methods: Thirteen individuals with PD (70.33 ± 6.
The inflammatory endotype in osteoarthritis: Reflections from the 2024 OARSI clinical trials symposium (CTS) with a special emphasis on feasibility for clinical development.
Osteoarthr Cartil Open
June 2025
Duke Molecular Physiology Institute and Department of Medicine, Duke University School of Medicine, Durham, NC, USA.
Objective: The inflammatory endotype is arguably one of the most well-established endotype in osteoarthritis (OA). While endotyping holds promise for advancing drug development, numerous potential challenges must be considered, addressed and resolved before successful clinical outcomes can be achieved.
Design: Since 2017, the Osteoarthritis Research Society International (OARSI) has hosted the Clinical Trials Symposium (CTS).
Interprofessional Discussion for Knowledge Transfer in a Digital "Community of Practice" for Managing Pneumoconiosis: Mixed Methods Study.
JMIR Form Res
March 2025
University of New Mexico Health Sciences Center, 1 University of New Mexico MSC 10 5550, Albuquerque, NM, 87131-0001, United States, 1 5052724751, 1 5052728700.
Background: Pneumoconiosis prevalence is increasing in the United States, especially among coal miners. Contemporaneously with an increased need for specialized multidisciplinary care for miners, there is a shortage of experts to fulfill this need. Miners' Wellness ECHO (Extension for Community Health Outcomes) is a digital community of practice based on interprofessional discussion for knowledge transfer.
View Article and Find Full Text PDFSevere Cutaneous Adverse Reaction to Lamotrigine: A Case of Stevens-Johnson Syndrome in a Psychiatric Patient.
Cureus
February 2025
Department of Pharmacology, Shri M P Shah Government Medical College, Jamnagar, IND.
Stevens-Johnson syndrome (SJS) is a severe and potentially life-threatening mucocutaneous reaction often triggered by medications. Antiepileptic drugs, particularly lamotrigine, are recognized as significant causative agents. Early identification and management are crucial to improve patient outcomes.
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