The ability of proteins to protect model liposome membranes from oxidation by hydroxyl and peroxyl free radicals was investigated.
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http://dx.doi.org/10.1179/135100002125000929 | DOI Listing |
Front Bioeng Biotechnol
January 2025
Department of Experimental Research and Guangxi Cancer Molecular Medicine Engineering Research Center and Guangxi Key Laboratory of Basic and Translational Research for Colorectal Cancer, Guangxi Medical University Cancer Hospital, Nanning, China.
An emerging strategy in cancer therapy involves inducing reactive oxygen species (ROS), specifically within tumors using nanozymes. However, existing nanozymes suffer from limitations such as low reactivity, poor biocompatibility, and limited targeting capabilities, hindering their therapeutic efficacy. In response, the PdRu@PEI bimetallic nanoalloys were constructed with well-catalytic activities and effective separation of charges, which can catalyze hydrogen peroxide (HO) to toxic hydroxyl radical (·OH) under near-infrared laser stimulation.
View Article and Find Full Text PDFSmall Methods
January 2025
Solid State and Structural Chemistry Unit (SSCU), Indian Institute of Science, Bengaluru, 560012, India.
Industrial production of hydrogen peroxide (HO) is energy-intensive and generates unwanted byproducts. Herein, an alternative production strategies of HO are demonstrated in a Zn-air and a photoelectrochemical cell. Employing an optimally produced reduced graphene oxide (rGO) electrocatalyst@air-cathode, an impressive power density of 320 Wm (geo = geometric area) is achieved along with a high HO production rate of 3.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
January 2025
Bio-Microfluidics Lab, Department of Electrical Engineering and Information Technology, Iranian Research Organization for Science and Technology, Tehran, Iran.
Water pollution, driven by a variety of enduring contaminants, poses considerable threats to ecosystems, human health, and biodiversity, highlighting the urgent need for innovative and sustainable treatment approaches. Ozone-based advanced oxidation processes (AOPs) have demonstrated significant efficacy in breaking down stubborn pollutants, such as organic micropollutants and pathogens, that are not easily addressed by traditional treatment techniques. This review offers an in-depth analysis of ozonation mechanisms, covering both the direct oxidation by ozone and the indirect reactions facilitated by hydroxyl radicals, emphasizing their effectiveness and adaptability across various wastewater matrices.
View Article and Find Full Text PDFEnviron Sci Technol
January 2025
Zachry Department of Civil & Environmental Engineering, Texas A&M University, College Station, Texas 77843, United States.
This study quantifies the contribution of the HO-dependent pathway to hydroxyl radical (OH) production from the photolysis of dissolved organic matter (DOM). OH formation rates were cross-validated using benzoate and terephthalate as probe compounds for diverse DOM sources (reference isolates and whole waters). Catalase addition revealed that the HO-dependent pathway accounts for 10-20% of the total OH production in DOM isolate materials, but no significant correlation was observed between ambient iron (Fe) concentrations and HO-dependent OH formation.
View Article and Find Full Text PDFEnviron Sci Technol
January 2025
State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, P. R. China.
The most well-known hydroxyl radical (OH)-generating system is the classic iron-mediated Fenton reaction. Thiourea has been considered as an efficient OH scavenger and is frequently used to study the role of OH in various biochemical and medical research studies. Here we found that the highly reactive OH can be produced from thiourea and HO through a metal-independent pathway, as measured by electron spin resonance (ESR) secondary radical spin-trapping and fluorescent methods.
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