Native and modified with ammonium ions alpha(2)-macroglobulin forms exhibit similar abilities to influence proliferative activity and secretion of immunoglobulins in cultures of human blood mononuclear cells in vitro. Effects of modified with ammonium ions alpha(2)-macroglobulin were more significant than those of native alpha(2)-macroglobulin. Revealed properties of native alpha(2)-macroglobulin could be conditioned by a partial modification of its structure with endogenous proteinases or cytokines, some of which were shown to be common affinants for both forms.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
alpha2-macroglobulin native
8
modified ammonium
8
ammonium ions
8
ions alpha2-macroglobulin
8
native alpha2-macroglobulin
8
alpha2-macroglobulin
5
immunoregulatory properties
4
properties alpha2-macroglobulin
4
native modified
4
alpha2-macroglobulin forms
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!