We developed a seminested PCR for the diagnosis of histoplasmosis that amplifies a portion of the Histoplasma capsulatum H antigen gene. This assay is highly sensitive and specific, being able to detect genomic material corresponding to less than 10 yeast cells without cross-reaction against other bacterial or fungal pathogens.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC153865 | PMC |
| http://dx.doi.org/10.1128/JCM.41.4.1753-1755.2003 | DOI Listing |
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