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Validating the Accuracy of Parkinson's Disease Clinical Diagnosis: A UK Brain Bank Case-Control Study.
Ann Neurol
January 2025
Research Unit of Neurology, Neurophysiology and Neurobiology, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.
Objective: Despite diagnostic criteria refinements, Parkinson's disease (PD) clinical diagnosis still suffers from a not satisfying accuracy, with the post-mortem examination as the gold standard for diagnosis. Seminal clinicopathological series highlighted that a relevant number of patients alive-diagnosed with idiopathic PD have an alternative post-mortem diagnosis. We evaluated the diagnostic accuracy of PD comparing the in-vivo clinical diagnosis with the post-mortem diagnosis performed through the pathological examination in 2 groups.
View Article and Find Full Text PDFThe impact of face masks on metacognition in sign language is mediated by proficiency.
Cogn Process
January 2025
Institute of Cognitive Sciences and Technologies (ISTC-CNR), Via Nomentana 56, 00161, Rome, Italy.
Face masks can impact processing a narrative in sign language, affecting several metacognitive dimensions of understanding (i.e., perceived effort, confidence and feeling of understanding).
View Article and Find Full Text PDFDeep learning based decision-making and outcome prediction for adolescent idiopathic scoliosis patients with posterior surgery.
Sci Rep
January 2025
Department of Orthopedics, Shanghai Changhai Hospital, Shanghai, 200433, China.
With the emergence of numerous classifications, surgical treatment for adolescent idiopathic scoliosis (AIS) can be guided more effectively. However, surgical decision-making and optimal strategies still lack standardization and personalized customization. Our study aims to devise proper deep learning (DL) models that incorporate key factors influencing surgical outcomes on the coronal plane in AIS patients to facilitate surgical decision-making and predict surgical results for AIS patients.
View Article and Find Full Text PDFAvoiding never events in orthopaedics theatres: a quality improvement project.
BMJ Open Qual
January 2025
Trauma & Orthopaedics, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK.
Never events in the operating room are a surgeon's nightmare, with an incidence rate of 54%. These events are highly stressful for theatre staff and significantly compromise patient safety. The aim of this project is to avoid never events in trauma and orthopaedic theatres by ensuring that theatre staff adhere to the surgical pause and imaging pause protocols through regular audits.
View Article and Find Full Text PDFExperimental and GEANT4 Simulated FEPE of NaI(Tl) Detector for Linear Sources.
Biomed Phys Eng Express
January 2025
Physics and Applied Mathematics, Pakistan Institute of Engineering and Applied Sciences, Qau, Islamabad, Islamabad, 44000, PAKISTAN.
The current study investigated the geometry, design and solid angle impacts on full energy peak efficiency (FEPE) of NaI(Tl) detectors for a line source. A line source is fabricated using 99mTc solution filled in a borosilicate glass tube of inner diameter 3 mm, tube wall thickness 2.5 mm and length 12.
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