Objective: To compare bioelectrical impedance analysis derived parameters in chronic maintenance dialysis patients to those obtained in National Health and Nutrition Examination Survey (NHANES) III.
Design: Cross-sectional nutritional surveillance study.
Setting: Hospital-based, not-for-profit chronic maintenance dialysis center.
Patients: A total of 913 chronic maintenance dialysis patients and a subset of 10,263 subjects from NHANES III who underwent bioelectrical impedance analysis. Independent (Predictor) Variables: Bioelectrical impedance parameters including resistance, reactance, phase angle, and total body capacitance.
Main Outcome Measures: Total body water, intracellular and extracellular water, body cell mass, fat free mass, fat mass.
Results: Relative to NHANES III, end-stage renal disease patients have lower resistance (3%), reactance (26%), phase angle (28%); and intracellular water (9%) values, whereas extracellular water content is 17% higher (P < .001). In addition, body cell mass, fat free mass, and fat mass were lower in end-stage renal disease patients when compared with NHANES III subjects (9%, 3%, and 12%, respectively; P < .001).
Conclusions: End-stage renal disease patients have a lower tissue mass than the general population and remain in a state of overhydration while on chronic maintenance dialysis therapy.
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http://dx.doi.org/10.1053/jren.2003.50022 | DOI Listing |
JMIR Ment Health
January 2025
Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, United States.
Background: Evidence-based digital therapeutics represent a new treatment modality in mental health, potentially providing cost-efficient, accessible means of augmenting existing treatments for chronic mental illnesses. CT-155/BI 3972080 is a prescription digital therapeutic under development as an adjunct to standard of care treatments for patients 18 years of age and older with experiential negative symptoms (ENS) of schizophrenia. Individual components of CT-155/BI 3972080 are designed based on the underlying principles of face-to-face treatment.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Pulmonary Diseases, Uludag University Faculty of Medicine, Bursa, Turkey.
Background: End-stage renal disease (ESRD) patients frequently experience protein-energy wasting (PEW), which increases their morbidity and mortality rates.
Objective: This study explores the effects of nutritional status and pulmonary function on the short- and long-term mortality of ESRD patients undergoing hemodialysis.
Materials And Methods: 67 consecutive ESRD patients on maintenance hemodialysis were included in the study.
Clin Transplant
February 2025
Department of Transplant Nephrology, Transplant Surgery Institute, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Calcineurin inhibitors have been the choice for maintenance immunosuppression (IS) in kidney transplant recipients (KTR), but they are associated with nephrotoxicity and metabolic side effects. We aim to compare the long-term outcomes of KTR on belatacept (bela) versus tacrolimus (tac) IS, in all KTRs and various subgroups. Using the UNOS-STAR files, we identified adult first-KTR from 2010 to 2022.
View Article and Find Full Text PDFInt J Chron Obstruct Pulmon Dis
January 2025
School of Translational Medicine, Monash University, Melbourne, VIC, Australia.
Purpose: Oral corticosteroids (OCS) are recommended for the treatment of exacerbations in people with COPD; however, high cumulative lifetime doses (≥1000mg prednisolone-equivalent) are associated with adverse health effects. This issue is well defined in asthma but is less well understood in COPD. The aim of this study was to examine cumulative OCS dispensed to people with COPD over 12 months.
View Article and Find Full Text PDFClin Cosmet Investig Dermatol
January 2025
Western University, London, ON, Canada.
Acne vulgaris is a globally prevalent dermatological condition associated with substantial physical and psychological burden. Although acne typically presents during adolescence, it is a chronic condition that also affects many adults. Despite the spectrum of treatments available for acne, limitations in tolerability and safety concerns can present challenges for the use of conventional medications in clinical practice.
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