The daily rhythms of cortisol (C) and serotonin (S) concentrations were investigated in saliva of children with chronic viral hepatitis HBV and HCV. The changes in chronostructure of C and S rhythms were revealed to depend on the viral type and an intensity of the liver inflammatory process. The circadian rhythms of C and S were found to be desynchronized which was manifested as quantitative (period) and qualitative (mesor value, amplitude of oscillations, daily acro- and miniphase) changes in the rhythm. The daily rhythm of S in children with an active and inactive HBV, as well as in those with an active HCV had the circadian character with a high mesor and an amplitude of oscillations, as compared to the control group. The transformation of the S rhythm was similar to the inactive HCV. Shifts in daily acrophase of the S rhythm were established for each clinic group. Daily C rhythm was not determined in the active HBV and HCV, either. The circadian C rhythm with daily acrophase was revealed for inactive HBV; the tendency to circadian rhythm of such type was marked for inactive HCV. The mesor of the above-mentioned groups didn't differ from the control.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Adverse childhood experiences and diurnal cortisol pattern and heart rate variability in adults.
Psychoneuroendocrinology
January 2025
School of Sport, Exercise and Health Sciences, Loughborough University, United Kingdom.
Dysregulation of hypothalamic-pituitary-adrenal axis (HPA axis) and of the autonomic nervous system may link stress throughout the life course with poorer health. This study aims to investigate whether multiple adverse childhood experiences have a long-term impact on markers of these systems - cortisol secretion and heart rate variability - in adulthood. Data were from the Whitehall II cohort study.
View Article and Find Full Text PDFAwakening not associated with an increased rate of cortisol secretion.
Proc Biol Sci
January 2025
Laboratory for Integrative Neuroscience and Endocrinology, University of Bristol, Bristol BS1 3NY, UK.
Cortisol is released upon activation of the hypothalamic-pituitary-adrenal axis, varies across the day, possesses an underlying diurnal rhythm and is responsive to stressors. The endogenous circadian peak of cortisol occurs in the morning, and increases in cortisol observed post-awakening have been named the cortisol awakening response (CAR) based on the belief that the act of waking up stimulates cortisol secretion. However, objective evidence that awakening induces cortisol secretion is limited.
View Article and Find Full Text PDFThe immune-inflammatory responses on the hypothalamic-pituitary-adrenal axis and the neurovascular unit in perioperative neurocognitive disorder.
Exp Neurol
January 2025
Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:
Perioperative neurocognitive disorders (PNDs) refer to a wide spectrum of cognitive impairment persisting days to even after a year postoperative with significant morbidity and mortality. However, despite much efforts involving perioperative managements, PNDs are still prevalent with no standard preventative and therapeutic strategy. To overcome PNDs, a better understanding of pathophysiology of PNDs is crucial and a large number of studies have proven that immune-inflammatory responses from surgical stress are involved in the abnormal activation of the hypothalamic-pituitary-adrenal (HPA) axis and destabilization of neurovascular unit (NVU) that lead to PNDs.
View Article and Find Full Text PDFEffects of time-of-day on the noradrenaline, adrenaline, cortisol and blood lipidome response to an ice bath.
Sci Rep
January 2025
Professorship of Exercise Biology, Department Health and Sport Sciences, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany.
While the effect of time-of-day (morning versus evening) on hormones, lipids and lipolysis has been studied in relation to meals and exercise, there are no studies that have investigated the effects of time-of-day on ice bath induced hormone and lipidome responses. In this crossover-designed study, a group of six women and six men, 26 ± 5 years old, 176 ± 7 cm tall, weighing 75 ± 10 kg, and a BMI of 23 ± 2 kg/mhad an ice bath (8-12 °C for 5 min) both in the morning and evening on separate days. Absence from intense physical exercise, nutrient intake and meal order was standardized in the 24 h prior the ice baths to account for confounders such as diet or exercise.
View Article and Find Full Text PDFGetting in Sync: When Do Babies' Cortisol Rhythms Start to Tick.
J Clin Endocrinol Metab
January 2025
AP-HP.Nord Université Paris Cité, Service d'Endocrinologie et Diabétologie Pédiatrique, Centre de Référence Maladies Endocriniennes Rares de la Croissance et du Développement, Hôpital Universitaire Robert-Debré, Paris 75019, France.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!