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Retrofitting massively parallel sequencing (MPS) for HLA-DQA1 and polymarker (PM) in forensic casework.
Int J Legal Med
January 2022
Department of Forensic Sciences, The George Washington University, 2100 Foxhall Road NW, Washington, DC, 20007, USA.
Genotype profiling has played a major role in forensics for decades. The technology for detection and discrimination has advanced substantially, from serology to DNA sequence analysis. Currently, there may be situations where there is a need for re-analysis of forensic DNA data that was produced using methodology that is no longer available.
View Article and Find Full Text PDFGenetic admixture of eight Mexican indigenous populations: based on five polymarker, HLA-DQA1, ABO, and RH loci.
Am J Hum Biol
January 2009
Instituto de Investigaciones Antropológicas, Universidad Nacional Autónoma de Mexico, Mexico District Federal, Mexico.
This study explores the genetic admixture of eight Mexican indigenous populations (Otomi-Ixmiquilpan, Otomi-Actopan, Tzeltales, Nahua-Milpa-Alta, Nahua-Xochimilco, Nahua-Zitlala, Nahua-Ixhuatlancillo, and Nahua-Coyolillo) on the basis of five PCR-based polymorphic DNA loci (LDLR, GYPA, HBGG, D7S8, GC), HLA_DQA1, and the blood groups ABO and Rh (CcDEe). Among the indigenous populations, the highest gene frequencies for O and D were 0.9703 and 1.
View Article and Find Full Text PDFHLA-DQA1 and polymarker in the Uros population from Peruvian Highland.
J Forensic Sci
November 2003
Laboratorio de Biotecnología e Ingeniería Genètica, Facultad de Ciencias Biológicas, Universidad Ricardo Palma, Lima, Perú.
Polymorphism of LDLR, GYPA, HBGG, D7S8, GC, HLA-DQA1, Ig-JH, D17S30, ApoB and D1S80 loci in northwestern Russians.
Forensic Sci Int
October 2003
Forensic Medicine Bureau of Leningrad District, Shkapin Street 36/40, St. Petersburg 198092, Russia.
Allele frequencies for polymarker, HLA-DQA1, Ig-JH, D17S30, ApoB and D1S80 loci and population genetic parameters were obtained from a sample of 501 unrelated individuals born in the northwestern Federal Region of Russia.
View Article and Find Full Text PDFHLA-DQA1 and polymarker locus allele frequencies in the northeast region of Colombia (Departments of Santander, Norte de Santander, Boyaca and Casanare).
J Forensic Sci
March 2003
Laboratorio de Genética, Facultad de Salud, Universidad Industrial de Santander, Bucaramanga, Colombia.
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