Objective: To estimate the burden (disability-adjusted life years) and economic impact (potential productivity loss) associated with trachomatous visual loss.
Data: National survey data on trachomatous blindness or visual impairment since 1980.
Methods: The primary results summarized studies for countries with known or suspected blinding trachoma within World Development Report demographic regions. The number of cases was based on the year 2000 population. The years of life with disability calculation used the age-sex distribution of trachomatous visual loss. The one-year potential productivity loss calculation used the agricultural value added per worker in 1998.
Results: Countries with known or suspected blinding trachoma have 3.8 million cases of blindness and 5.3 million cases of low vision and a potential productivity loss of 2.9 billion US dollars (1995 US dollars). Prevalent cases of trachomatous visual loss yield 39 million lifetime DALYs.
Conclusions: For resource allocation, the burden of disease can be compared with the expected costs of eradication of trachomatous blindness.
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http://dx.doi.org/10.1076/opep.10.2.121.13899 | DOI Listing |
Ophthalmic Epidemiol
December 2024
Department of Ophthalmology and Schepens Eye Research Institute, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.
Purpose: To report the design of FLuorometholone as Adjunctive MEdical therapy for TT surgery (FLAME) trial.
Design: Parallel design, double-masked, placebo-controlled clinical trial with 1:1 randomization to fluorometholone 0.1% eye drops twice daily or placebo twice daily for 4 weeks in eyes undergoing trachomatous trichiasis (TT) surgery for assessing the efficacy, safety, and cost-effectiveness of fluorometholone 0.
PLoS Negl Trop Dis
November 2024
Global Neglected Tropical Diseases Programme, World Health Organization, Geneva, Switzerland.
Eye Vis (Lond)
November 2024
Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore, Singapore.
Over the past few decades, the expanded applications of in-vivo confocal microscopy (IVCM) have greatly enhanced the knowledge of a variety of conjunctival diseases. IVCM allows non-invasively detailed observation of tarsal, palpebral and bulbar conjunctiva, from the superficial to the substantia propria at the cellular level. IVCM has been shown as a powerful tool for the assessment of morphological changes in both physiological and pathological conditions.
View Article and Find Full Text PDFPLoS Negl Trop Dis
September 2024
Department of Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.
Microorganisms
July 2024
School of Medicine, University of Crete, 715 00 Heraklion, Greece.
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