Cardioprotective effect of trimetazidine during thrombolytic therapy in patients with acute myocardial infarction.

Bull Exp Biol Med

Laboratory of Molecular and Cell Pathology and Genetic Diagnostics, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia.

Published: December 2002

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We studied the cardioprotective effect of anti-ischemic drug trimetazidine in the thrombolytic therapy of acute myocardial infarction. Trimetazidine (60 mg/day) effectively inhibits lipid peroxidation and moderates reperfusion damage to the myocardium assessed by ECG, QRS index of damaged heart, and release of creatine phosphokinase into circulation.

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http://dx.doi.org/10.1023/a:1022961112062DOI Listing

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