Function of Ca-pump in sarcoplasmic reticulum of rat myocardium during adaptation to electromagnetic field.

We studied the effect of adaptation to electromagnetic field on functional state of Ca-pump in sarcoplasmic reticulum, intensity of lipid peroxidation, and energy metabolism in rat myocardium. Membrane viscosity was assessed in crude preparation of myocardial sarcoplasmic reticulum. Adaptation to electromagnetic field did not change the rate of endogenous respiration, including ouabain-sensitive respiration, but potentiated coupling between catalytic activity and Ca-transporting capacity of Ca-pump. It is hypothesized that modification of structural and functional properties of the membrane due to inhibition of free radical processes increases functional activity of Ca-pump in sarcoplasmic reticulum.