Torsion of undescended testis in a man with Down's syndrome.

Int J Urol

Department of Urology, St Andrew's Patras Regional Hospital, School of Medicine, Elefteriou Venizlou 30, 26 500, Agios Vassilios of Patras, Greece.

Published: April 2003

Undescended testis is one of the most common disorders in Down's syndrome. We present an extremely rare case of torsion of an inguinal undescended testis in a 35-year-old patient with Down's syndrome. Surgical exploration revealed a rotated gangrenous testis, radical orchiectomy was performed, and pathological examination confirmed the diagnosis of testicular torsion.

Download full-text PDF

Source
http://dx.doi.org/10.1046/j.0919-8172.2003.00600.xDOI Listing

Publication Analysis

Top Keywords

undescended testis
12
down's syndrome
12
torsion undescended
4
testis
4
testis man
4
man down's
4
syndrome undescended
4
testis common
4
common disorders
4
disorders down's
4

Similar Publications

Long noncoding RNAs (LncRNAs) play essential roles in numerous biological processes in mammals, such as reproductive physiology and endocrinology. Cryptorchidism is a common male reproductive disease. Circadian rhythms are actively expressed in the reproductive system.

View Article and Find Full Text PDF

Spigelian hernia and cryptorchidism syndrome in children is increasingly reported in the literature. A variety of phenotypes have been reported, so diagnostic approaches and operative techniques remain poorly defined. The case of an infant male who presented with a left spigelian hernia and ipsilateral cryptorchidism who was initially misdiagnosed with an ectopic inguinal testis is presented.

View Article and Find Full Text PDF

Cryptorchidism, the absence of one or both testicles in the scrotum, is the most common anomaly of genitourinary tract in males. The pathogenesis of undescended testes is unknown however the role of inflammation, tissue remodeling and oxidative stress is postulated. The aim of this study was to explore the role of HSP-70, MMP-3, MMP-17 and IL-8 in possible pathogenic pathways connected with cryptorchidism.

View Article and Find Full Text PDF
Article Synopsis
  • Cryptorchidism is a common congenital condition in newborn males where one or both testes fail to descend into the scrotum, leading to potential infertility due to azoospermia.
  • Research using a mouse model of surgically induced cryptorchidism revealed changes in the epigenetic markers H3K27me3 and H3K9me3 in spermatogonial cells, with a specific loss of H3K27me3 linked to gene activation related to development and apoptosis.
  • The study indicates that elevated temperatures may enhance the activity of enzymes that demethylate H3K27, contributing to mRNA dysregulation and potentially impacting spermatogonial function.
View Article and Find Full Text PDF

The Role of Laparoscopy in Managing Impalpable Undescended Testes in a Tertiary Hospital.

Mymensingh Med J

January 2025

Dr Mohammad Showkot Ali, Assistant Professor, Department of Pediatric Surgery, Mymensingh Medical College (MMC), Mymensingh, Bangladesh; E-mail:

One of the most prevalent congenital defects in boys is undescended testes. Ultrasound is commonly employed to locate the testis in cases of impalpable testes, which frequently yields false-negative results. Laparoscopy has gained widespread acceptance recently for managing impalpable testes.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!