Venous leg ulcers may affect up to 3.5% of the general patient population. The purchase price for dressing is not the true indication of cost effectiveness of any given method of care; rather cost is a combination of the price of the dressing plus labor required. Total cost equals nursing time, physician time, hospital stay, home-health costs, risks, and costs of complications (for example, infection), and the frequency of dressing changes.
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ACS Appl Mater Interfaces
January 2025
College of pharmacy, Xinxiang Medical University, Xinxiang, Henan 453003, PR China.
This study introduced a hydrogel dressing, termed SODex-gel, which was constructed by establishing Schiff base and hydrogen bonds with the precursors of oxidized dextran (ODex) and succinic dihydrazide (SD)-modified sodium alginate (SD--SA). Through comprehensive and studies, the adhesive properties, self-healing capabilities, hemostatic potential, and wound healing efficacy of the SODex-gel dressing were meticulously evaluated. The H NMR, FTIR, and TGA analyses confirmed the fabrication of the SODex-gel dressing and its constituent elements.
View Article and Find Full Text PDFInt Wound J
December 2024
Unit 7, Pioneer, Wound Healing and Lymphoedema Centres, Sussex, UK.
The objective of the study was to show the clinical performance and cost-effectiveness of a Silicone foam dressing with 3DFit™ Technology compared to current standard of care. This was an open-labelled, two-arm, randomised controlled multicentre study conducted from February to December 2023. One hundred and two participants with an exuding, non-infected and chronic ulcer were randomised in a 1:1 fashion and treated with either a Silicone foam with 3DFit™ Technology or standard of care (a filler combined with a secondary dressing), stratified by venous leg ulcers and diabetic foot ulcers.
View Article and Find Full Text PDFVascular
December 2024
Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Background: Patients suffering from lower extremity venous ulcers typically undergo prolonged dressing changes, entailing extended treatment cycles and significant costs, creating an urgent need for effective continuous care. There is scarce literature reporting on the preferences and requirements for wound care within continuous care services for such conditions. Discrete choice experiments serve as an innovative method to elicit patient preferences, where the development of attributes and levels is a critically important process.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
College of Sericulture, Textile and Biomass Sciences, State Key Laboratory of Resource Insects, Southwest University, Chongqing 400715, China. Electronic address:
Scar formation and chronic refractory wounds pose a significant threat to public health, with abnormal immune regulation as a key characteristic. However, topography, a crucial factor influencing immune responses, has not been adequately considered in the design of wound dressings. In this study, we constructed a hierarchical structure on silk fibroin (SF) films by combining soft lithography and femtosecond laser ablation, without altering the intrinsic properties of SF.
View Article and Find Full Text PDFJ Wound Care
December 2024
Donald and Barbara Zucker School of Medicine, Hofstra/Northwell, Hempstead, NY, US.
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