The aim of this study was to investigate whether apamin-sensitive K(+)channels play a role in the NO induced relaxation of the human pregnant myometrium. Concentration-response curves for sodium nitroprusside (SNP) (10(-9)-10(-4)M) were constructed in the absence and presence of 10(-8)M apamin and 10(-7)M charybdotoxin (CTX). Preincubation with apamin resulted in a significant attenuation of the relaxation caused by SNP, while pre-treatment with CTX insignificantly decreased the SNP induced relaxation. Our findings suggest that apamin-sensitive K(+)channels exist in the human pregnant myometrium and play a role in modulation of the myometrium response to NO donors
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Freestanding birth centers (FBCs) in Brazil are regulated to provide care for women with a straightforward pregnancy. The systematization of the literature on FBCs can broaden our knowledge of these facilities. We conducted a scoping review to answer the following research question: "What are the characteristics of the model of care in freestanding birth centers in Brazil?".
View Article and Find Full Text PDF[Self-government processes of mothers in the context of the Brazilian Rede Cegonha Program].
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Departamento de Saúde Coletiva, Faculdade de Ciências Médicas, Unicamp. Campinas SP Brasil.
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Universidade Federal de São Paulo, Departamento de Enfermagem na Saúde da Mulher, São Paulo, SP, Brasil.
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PLoS One
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Department of Statistics, University of Dhaka, Dhaka, Bangladesh.
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