In this study we investigated the role of the bacterial flagellum in Burkholderia pseudomallei entry to Acanthamoeba astronyxis trophozoites. B. pseudomallei cells were tethered to the external amoebic surface via their flagella. MM35, the flagellum-lacking fliC knockout derivative of B. pseudomallei NCTC 1026b did not demonstrate flagellum-mediated endocytosis in timed coculture, confirming that an intact flagellar apparatus assists B. pseudomallei entry into A. astronyxis.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC152052 | PMC |
| http://dx.doi.org/10.1128/IAI.71.4.2280-2282.2003 | DOI Listing |
Publication Analysis
Top Keywords
burkholderia pseudomallei
8
acanthamoeba astronyxis
8
pseudomallei entry
8
pseudomallei
5
flagellum-mediated adhesion
4
adhesion burkholderia
4
pseudomallei precedes
4
precedes invasion
4
invasion acanthamoeba
4
astronyxis study
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!