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We report a child with Down's syndrome in whom metrorrhagia and precocious puberty revealed primary autoimmune hypothyroidism. The patient had a decreased growth velocity, exaggerated weight gain, bone age delay, and bilaterally enlarged multicystic ovaries. Delays in the diagnosis and treatment of hypothyroidism can lead to this peculiar presentation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1719525 | PMC |
| http://dx.doi.org/10.1136/adc.88.4.330 | DOI Listing |
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