AI Article Synopsis

  • A study examined 29 patients with laboratory-confirmed West Nile virus (WNV) encephalitis, tracking their immune response over time.
  • Of the 12 patients who were tested after about 500 days, 60% (7 patients) still showed the presence of anti-WNV IgM antibodies.
  • The findings suggest that medical professionals need to be careful when evaluating serological tests for WNV in patients who test positive early in the season.

Article Abstract

Twenty-nine laboratory-confirmed West Nile virus (WNV encephalitis patients were bled serially so that WNV-reactive immunoglobulin (Ig) M activity could be determined. Of those patients bled, 7 (60%) of 12 had anti-WNV IgM at approximately 500 days after onset. Clinicians should be cautious when interpreting serologic results from early season WNV IgM-positive patients.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958550PMC
http://dx.doi.org/10.3201/eid0903.020531DOI Listing

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