Experiments were carried out on 19 adult cats with chronic brain stem transections at the level of the foremost border of the supperior colliculus. High-frequency electric stimulation of the posterior hypothalamus produced in these cats desynchronization of electrical activity in different parts of the neocortex. A predominant influence from the posterior hypothalamus on the electrical activity of frontal lobes was observed. On the basis of the obtained data, it is suggested that the influences from posterior hypothalamus elicit neocortical activation via thalamic nuclei.
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Vitam Horm
January 2025
Clinical Research Center, Murayama Medical Center, Musashimurayama, Japan.
The hypothalamus is the gray matter of the ventral portion of the diencephalon. The hypothalamus is the higher center of the autonomic nervous system and is involved in the regulation of various homeostatic mechanisms. It also modulates respiration by facilitating the respiratory network.
View Article and Find Full Text PDFInt J Mol Sci
January 2025
Laboratory of Neuroendocrinology and In Situ Hybridization, Department of Anatomy, Histology and Embryology, Semmelweis University, H1094 Budapest, Hungary.
The ability to reproduce depends on metabolic status. In rodents, the ventral premammillary nucleus (PMv) integrates metabolic and reproductive signals. While leptin (adiposity-related) signaling in the PMv is critical for female fertility, male reproductive functions are strongly influenced by glucose homeostasis.
View Article and Find Full Text PDFBrain Sci
January 2025
Department of Physiology, College of Medicine, Yonsei University, Seoul 03722, Republic of Korea.
The significant correlation between ancient medicinal practices and brain function marks a revolutionary frontier in the field of neuroscience. Acupuncture, a traditional oriental medicine, can affect brain regions, such as the hypothalamus, anterior cingulate, posterior cingulate, and hippocampus, and produces specific therapeutic effects, such as pain relief, suppression of hypertension, and alleviation of drug addiction. Among the brain regions, the hypothalamus, a small yet critical region in the brain, plays a pivotal role in maintaining homeostasis by regulating a wide array of physiological processes, including stress responses, energy balance, and pain modulation.
View Article and Find Full Text PDFInflamm Res
January 2025
Medical Faculty and University Hospital, Institute of Neural and Sensory Physiology, Heinrich Heine University Düsseldorf, 40225, Düsseldorf, Germany.
Background: Adenosine, an ATP degradation product, is a sleep pressure factor. The adenosine 1 receptor (A1R) reports sleep need. Histaminergic neurons (HN) of the tuberomamillary nucleus (TMN) fire exclusively during wakefulness and promote arousal.
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