The choice of the optimum technique of the sanitation procedure in treatment of acute necrotizing pancreatitis (ANP) is now one of the most disputable problems. Clinical estimation of the efficiency of various operative techniques of treatment of ANP at various stages of disease has been made. In the aseptic phase laparoscopic decompression of the pancreas is indicated when the patient has evident hemorrhagic parapancreatitis. In the phase of septic sequestration of ANP the optimum method of minimally invasive surgical intervention is considered to be minilaparotomy which is expedient for abscesses of small volume, lipid abscesses of any volume with the minimal content of necrotizing tissues as the first step of sanitation in critical patient. High quantity of the necrotizing tissues in the zone of the destructive focus requires traditional laparotomy of the abscess under conditions of preventive maintenance of the endotoxic shock.
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Endocrinol Diabetes Metab Case Rep
January 2025
Summary: Palmoplantar keratoderma (PPK), characterised by excessive epidermal thickening of the skin on the palms and/or plantar surfaces of the feet, can be hereditary or acquired. Here, we report a case of a 53-year-old woman with a history of sub-optimally controlled diabetes mellitus presenting with fevers and decreased Glasgow Coma Scale (GCS) to a tertiary hospital. She was diagnosed with diabetic ketoacidosis (DKA), with blood glucose at 40 mmol/L and ketones at 7 mmol/L, in the setting of a methicillin-sensitive Staphylococcus aureus necrotising soft tissue back infection.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Institute for Stroke and Dementia Research (ISD), University Hospital, LMU, Munich, Germany.
Background: The myelin sheath around axons is of fundamental importance for signal transduction. Myelin is reduced in white matter hyperintensities (WMH), which occur in both small vessel disease (SVD) and Alzheimer's disease (AD), giving rise to the question to what extent myelin is reduced in these diseases. Here, we employed an advanced MRI based method to assess myelin independently from a major confounding factor, i.
View Article and Find Full Text PDFImmun Inflamm Dis
January 2025
School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People's Republic of China.
Background: Traumatic spinal cord injury (SCI) is an incurable condition that is the largest cause of disability. In previous studies, Isosteviol sodium (STVNa) has been shown to protect rats against acute focal cerebral ischemia; however, the effects of STVNa on SCI recovery in rats remain unknown.
Methods: STVNa was given intraperitoneally after SCI to see if it had any neuroprotective benefits.
Alzheimers Dement
December 2024
German Center for Neurodegenerative Diseases (DZNE), Munich, Bavaria, Germany.
Background: The myelin sheath around axons is of fundamental importance for signal transduction. Myelin is reduced in white matter hyperintensities (WMH), which occur in both small vessel disease (SVD) and Alzheimer's disease (AD), giving rise to the question to what extent myelin is reduced in these diseases. Here, we employed an advanced MRI based method to assess myelin independently from a major confounding factor, i.
View Article and Find Full Text PDFDis Aquat Organ
January 2025
Mississippi Aquarium, Department of Veterinary Services, Gulfport, Mississippi 39502, USA.
This report documents complications in false pilchard Harengula clupeola and scad Decapterus macarellus associated with a salinomycin (60 mg kg-1) and amprolium (100 mg kg-1) gel feed treatment, along with prolonged temperature increase, for an Enteromyxum leei outbreak in a salt water, mixed species, public aquarium exhibit. Shortly after administration, a mass mortality event ensued where hundreds of false pilchards and a few scad died. Medicated gel feed was noted within the gastrointestinal tracts of all affected fish.
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