[Clinical practice guidelines for diagnosis and treatment of osteoporosis].

The Japanese Society for Bone and Mineral Research organized a committee to make a new criteria of diagnosis for osteoporosis in 2000. In the criteria, cases who show atraumatic fractures in demineralized bone are made a diagnose of osteoporosis. In the cases who show no atraumatic fractures, patients whose bone mineral densities are less than 70% of mean density of young adult persons or whose X-ray films indicate coarse or unclear longitudinal trabeculae in vertebral body, are also made a diagnose of osteoporosis. A guideline for treatment of osteoporosis had been present in 1998, and another committee make ready for a new guideline in 2002. The new guideline is presenting as (1) increase in oral calcium intake and inpact exercise, prevention of fall, and wearing of external hip protector are recommended in addition to pharmacological agents, (2) in pharmacological agents, estrogens, calcitonins and bisphosphonates are effective to the patients with rapid bone loss, and (3) vitamin D3 derivatives and vitamin K2 are recommended for the patients with diminished bone formation.