High resolution computer simulations of two-dimensional convection using the anelastic approximation are presented. These calculations span Rayleigh numbers from 10(8)-10(12) for Prandtl number equal to unity, with the fluid density decreasing by a factor of 12 from the bottom to the top of the convection region. This range covers several decades in the "hard" turbulent regime. While many studies of this sort have been conducted for the Boussinesq approximation (i.e., no density stratification), we use the anelastic approximation with a significant density stratification in this turbulent regime. The convection is dominated by a large-scale coherent flow composed of ascending and descending superplumes. We find a power law exponent of 0.28 for the Nusselt-Rayleigh number scaling and a power law with exponent of 0.50 for the Reynolds-Rayleigh number scaling for the entire parameter space studied. These values are very similar to those determined experimentally and analytically for convection with no density stratification.
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http://dx.doi.org/10.1103/PhysRevE.67.026315 | DOI Listing |
BJU Int
January 2025
Faculty of Social Sciences (Health Sciences), Prostate Cancer Research Center, Tampere University, Tampere, Finland.
Objective: To assess the association between prostate-specific antigen (PSA) density (PSAD) and prostate cancer mortality after a benign result on systematic transrectal ultrasonography (TRUS)-guided prostate biopsy.
Patients And Methods: This retrospective study used data from the Finnish Randomised Study of Screening for Prostate Cancer (FinRSPC) collected between 1996 and 2020. We identified men aged 55-71 years randomised to the screening arm with PSA ≥4.
Quant Imaging Med Surg
January 2025
Department of Nuclear Medicine, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Background: Although F-prostate-specific membrane antigen-1007 (F-PSMA-1007) positron emission tomography/computed tomography (PET/CT) and multiparametric magnetic resonance imaging (mpMRI) are good predictors of prostate cancer (PCa) prognosis, their combined ability to predict prostate-specific antigen (PSA) persistence has not been thoroughly evaluated. In this study, we assessed whether clinical, mpMRI, and F-PSMA-1007 PET/CT characteristics could predict PSA persistence in patients with PCa treated with radical prostatectomy (RP).
Methods: This retrospective study involved consecutive patients diagnosed with PCa who underwent both preoperative mpMRI and PSMA PET/CT scans between April 2019 and June 2022.
Curr Med Chem
January 2025
Laboratory for Research on Molecular Mechanisms of Longevity, Faculty of Biology and Biotechnology, HSE University, Moscow, Russia.
Aims: The purpose of this study was to investigate the prognostic significance of cholesterol uptake genes in predicting the survival of breast cancer patients.
Background: Cholesterol plays a crucial role in the homeostasis of tumor cells. It is known that cholesterol levels can influence important parameters of the disease, such as sensitivity to therapy, progression, and metastasis of cancer.
BMC Med
January 2025
Health and Social Research Center, Universidad de Castilla-La Mancha, Cuenca, Spain.
Background: Recent evidence from both randomized controlled trials and cohort studies in adults suggests that plasma remnant cholesterol (RC) levels predict cardiovascular disease. In children, studies are scarce, although high levels of RC might represent a marker of early atherosclerotic damage. Thus, the aim of this study was to explore the cardiometabolic risk associated with RC, which extends beyond low-density lipoprotein cholesterol (LDL-c) in children.
View Article and Find Full Text PDFIntroduction: Epilepsy is one of the most common neurological conditions worldwide, with large variation in prevalence across Sub-Saharan Africa countries. Northern Uganda is one of the poorest areas of the country and has seen high density of pigs and prevalence of Taenia solium, a zoonotic tapeworm transmitted which cause neurocysticercosis in humans. The objective of this study was to estimate the population-level prevalence of active epilepsy in 25 sub-counties of northern Uganda.
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