While knowledge about peripheral arterial disease (PAD) appears well disseminated, the condition still goes largely undiagnosed and untreated. In PART 1 of this paper, we summarized the diagnosis, epidemiology and risk factors for PAD. Non-invasive treatment involves management of risk factors and targeted drug therapy. Invasive strategies include angioplasty, angiogenesis and surgery. Dealing with both the structural factors (physical plaque morphology) and functional ones (endothelial function) are important in effectively managing PAD. This paper (PART 2) deals with the management (medical and surgical) of PAD.
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