Evaluation of antidiabetic effect of Momordica cymbalaria fruit in alloxan-diabetic rats.

Fitoterapia

Department of Biochemistry, School of Biological and Earth Science, Sri Venkateswara University, Tirupathi 517502, India.

Published: February 2003

The oral treatment with the aqueous extract of Momordica cymbalaria fruit (MC) (0.5 g/kg) for 6 weeks showed a significant antihyperglycemic as well as antihyperlipidemic effects in the alloxan-induced diabetic rats.

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0367-326x(02)00297-6DOI Listing

Publication Analysis

Top Keywords

momordica cymbalaria
8
cymbalaria fruit
8
evaluation antidiabetic
4
antidiabetic momordica
4
fruit alloxan-diabetic
4
alloxan-diabetic rats
4
rats oral
4
oral treatment
4
treatment aqueous
4
aqueous extract
4

Similar Publications

The fruit and other parts of Momordica cymbalaria are known to have medicinal properties. The study investigates the chemical composition and functional groups of M. cymbalaria fruits to assess the insecticidal potential of its bioactive metabolites.

View Article and Find Full Text PDF

Hook F. (MC), belonging to the family Cucurbitaceae, is a plant with several biological activities. This detailed, comprehensive review gathers and presents all the information related to the geographical distribution, morphology, therapeutic uses, nutritional values, pharmacognostic characters, phytochemicals, and pharmacological activities of MC.

View Article and Find Full Text PDF

Heavy metals have played a great role in the genesis of the present-day civilization. Human beings are affected when these metals are added to the food chain. Although these are the most important plant nutrients, they are phytotoxic at high concentrations.

View Article and Find Full Text PDF

Mcy protein, isolated from the fruits of Momordica cymbalaria, was shown to have antihyperglycemic, antihyperlipidemic activities along with renal as well as hepatoprotective activities in streptozotocin-induced diabetic rats. Mcy protein was shown to have insulin-like structure and/or function and/or insulin secretagogue activity. Hence, the present study was conducted to elucidate the molecular mechanism whereby Mcy protein elicits its therapeutic role and also to know whether the Mcy protein has any structural and functional similarity with insulin.

View Article and Find Full Text PDF

Male reproductive dysfunction is one of the common complications of diabetes mellitus that causes infertility. This study was designed to investigate the protective effect of () extracts on diabetes mediated reproductive toxicity in male Wistar rats. The induction of diabetes was performed using a single intraperitoneal injection of alloxan (120 mg/kg).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!