Percutaneous vasal sperm aspiration and intrauterine insemination for infertile males with anejaculation.

Objective: To explore the effectiveness of percutaneous vasal sperm aspiration (PVSA) in combination with intrauterine insemination (IUI) to treat infertile men with anejaculation.

Design: Clinical study.

Setting: Department of reproductive endocrinology and andrology of a family planning research clinic.

Patient(s): Twenty-six anejaculatory infertile men.

Intervention(s): Spermatozoa obtained from the vas deferens by percutaneous aspiration were incubated in sperm preparation medium.

Main Outcome Measure(s): Sperm quality by PVSA and pregnancy outcome.

Result(s): Thirty-four PVSA-IUI procedures were performed in 26 men with anejaculation. Nineteen pregnancies were achieved (pregnancy rate, 73.1%). Mean (+/-SD) values for sperm variables were as follows: motility, 78.6% +/- 14.2%; progressive motility, 60.4% +/- 11.2%; density, 37.6 +/- 13.2 x 10(6) cells/mL; total count, 35.2 +/- 13.2 x 10(6) cells; and abnormal sperm, 18.6% +/- 7.6%.

Conclusion(s): Percutaneous vasal sperm aspiration may obtain high-motility sperm, and PVSA plus IUI is an effective treatment for male infertility with anejaculation.