In industrialized countries, male excess is generally found in early deaths, despite the overall decrease in mortality. We studied the association between sex and some factors generally considered crucial for babies' survival, such as mother's age and education, birth order, and gestational age, in order to gain insight into the causes underlying the persisting higher vulnerability of male sex in early life. The analysis was performed on babies dying during the perinatal period. These were subdivided into those who were stillborn and those who died during the first week of extrauterine life. A higher male excess among babies dying during the neonatal period than among those who were stillborn was always found in all classes of all factors. The finding of such generalized male overmortality in the early extrauterine period of life, together with the patterns shown by the temporal sex ratio in stillbirths and in early deaths, supports the hypothesis of a postponement of male risk from late fetal into neonatal life.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1353/hub.2003.0012 | DOI Listing |
Wounds
December 2024
Smith+Nephew, Watford, Hertfordshire, UK.
Background: Achievement of moisture balance can be a critical factor affecting time to closure of nonhealing wounds, and dry wounds can take much longer to heal than those with high exudate levels. Whether the goal of management is to donate moisture to the wound or control excessive fluid until the cause has been identified and addressed, choice of dressing and other wound management products can affect nursing resources, clinical outcomes, concordance, and quality of life for the patient.
Case Reports: The cases discussed illustrate differences in management approaches for dry and wet wounds and show how clinician support tools (eg, tissue type, infection/inflammation, moisture imbalance, epithelial edge advancement [TIME] clinical decision support tool) can facilitate treatment decisions.
JBJS Case Connect
January 2025
Department of Orthopaedic Surgery, Kyoto City Hospital, Kyoto, Japan.
Case: We present 3 cases demonstrating radiographic posterior subluxation in lateral functional radiographs taken in the flexed-seated position. Two of the patients were asymptomatic, and 2 showed the posterior translation of the femoral head, which is almost a dislocation, with spontaneous reduction. The subluxation can occur not only in patients after lumbar fusion surgery but also in patients with relatively normal lumbar spine due to excessive hip flexion.
View Article and Find Full Text PDFAllergol Immunopathol (Madr)
January 2025
Department of Pediatrics, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zheiiang, China.
To illustrate the potential of mesenchymal stem cell-derived exosomes (MSC-Exos) in mitigating septic lung injury by reducing the excessive formation of neutrophil extracellular traps (NETs), a mouse model of septic lung injury was induced through cecal ligation and puncture (CLP). The mice received intraperitoneal injections of MSC-Exos. Post injection, pathological alterations of the lung tissue were evaluated through HE staining, and the levels of inflammatory markers in each mouse group at various time points were assessed using ELISA kits.
View Article and Find Full Text PDFArch Dermatol Res
January 2025
Medical Intensive Care Unit, Zhangzhou Hospital Affiliated of Fujian Medical University, Zhangzhou Municipal Hospital of Fujian Province, Zhangzhou City, Fujian Province, China.
Background: The fibrosis of pathologic scar (PS) is formed by the excessive deposition of extracellular matrix, resulting in an abnormal scar. Recent clinical tests have indicated that the regulation of PS fibroblast cells (PSF cells) proliferation can serve as an intervention measure for PS. Our work aimed to elucidate the specific mechanism of action of TCF4 on the progression of PS fibrosis.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Thai Red Cross Emerging Infectious Diseases Health Science Centre, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Background: The validation of blood-based biomarkers presents a promising role in Alzheimer's disease (AD) diagnosis owing to their accessibility and diminished invasiveness. However, despite awareness of confounding factors like kidney function, inaccuracies persist in AD diagnosis using plasma p-tau. Notably, diverse conditions that modify blood-brain barrier (BBB) permeability have been linked to high plasma p-tau levels, irrespective of AD pathophysiology.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!