The mode of action of the secondary metabolite chlorofusin, which antagonises the interaction between p53 and MDM2, involves direct binding to the N-terminal domain of MDM2.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/b211889k | DOI Listing |
Publication Analysis
Top Keywords
binding inhibitor
4
inhibitor p53/mdm2
4
p53/mdm2 interaction
4
interaction mdm2
4
mdm2 mode
4
mode action
4
action secondary
4
secondary metabolite
4
metabolite chlorofusin
4
chlorofusin antagonises
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!